Ruger Mark IV 22 45 22 LR 4 4IN Threaded Barrel 2X10RD
About this product
Important note before anything else: this is a complete .22 LR pistol, not a barrel or accessory part — despite any category mislabeling elsewhere, model 40149 is a full Ruger Mark IV 22/45 Tactical handgun, shipping with two 10-round magazines and a threaded 4.4-inch bull barrel. It combines Ruger's simplified Mark IV takedown system with the 22/45 line's 1911-style grip angle, giving shooters familiar 1911 ergonomics in a rimfire training or plinking pistol.
What does "22/45" mean, and why does the grip feel different from a standard Mark IV?
Ruger's 22/45 designation refers to the grip frame's angle, which is shaped to mimic a 1911's grip geometry rather than the standard Mark-series grip angle. That makes the 22/45 line a popular choice for 1911 shooters who want a low-cost .22 LR trainer that points and feels similar to their centerfire carry or competition pistol, letting them practice trigger control and follow-through without the cost of centerfire ammunition.
What does the threaded barrel support?
The 4.4-inch stainless bull barrel is threaded 1/2x28 with a 1:16-inch twist and 6-groove rifling, allowing attachment of a suppressor or other compatible muzzle device, subject to all applicable federal and state regulations. For shooters interested in a quiet, low-recoil training or pest-control setup, a threaded .22 LR pistol paired with a rimfire suppressor is one of the most popular combinations in the rimfire world, given how effectively suppressors work on subsonic .22 LR ammunition.
What safety features does this pistol include?
Beyond the ambidextrous manual safety, the Mark IV 22/45 Tactical includes a magazine disconnect, which prevents the pistol from firing when the magazine is removed even if a round remains in the chamber — an added layer of safety that some shooters specifically look for in a training or family-range pistol. Picatinny rails on both the top and bottom of the frame allow mounting an optic and a light or laser respectively, rounding out a fairly full-featured accessory setup for a rimfire pistol at this price point.
How does Ruger's one-button takedown work on this model?
Like other current Mark IV pistols, the 22/45 Tactical uses Ruger's redesigned one-button takedown, letting the upper receiver tilt up and separate from the grip frame for cleaning without needing to realign an internal pin by feel — a meaningful improvement over older Mark-series pistols, which were notorious among owners for fiddly, frustrating disassembly.
Who is this pistol best suited for?
1911 shooters looking for an affordable, low-recoil trainer with a familiar grip angle, suppressor enthusiasts wanting a threaded rimfire host, and anyone who wants a full-featured Picatinny-railed .22 LR pistol for target practice are all strong fits for the 22/45 Tactical. Buyers should keep in mind this ships as a complete, ready-to-fire handgun rather than any kind of barrel or parts kit.
As a firearm, this pistol ships to a licensed FFL dealer rather than to your home address; you'll complete your background check and required paperwork there before taking possession. California buyers should confirm current compliance status for this model with their FFL before ordering.
How does the 22/45 Tactical compare to Ruger's standard Mark IV Tactical model?
Ruger also sells a standard Mark IV Tactical built on the traditional Mark-series grip angle rather than the 1911-style 22/45 frame, so the choice between the two comes down largely to which grip geometry feels more natural in your hand and which pistol you're using it to train alongside. Both share the same threaded 4.4-inch barrel, one-button takedown, and Picatinny rail layout, so the decision is primarily about grip ergonomics rather than any functional difference between the two configurations.
FFL transfer required
This item is a firearm and ships only to a licensed FFL dealer, never to a home address. At checkout, enter your preferred dealer as the shipping address, or leave it blank and we will assign a licensed dealer near you at no extra cost. You complete the background check and paperwork with the dealer when you pick up.
California buyers: handguns must be on the California roster for delivery to a California FFL, a Firearm Safety Certificate (FSC) and DROS are handled at the dealer, and the 10-day waiting period applies. Out-of-state buyers receive the firearm through their own local FFL under their state's rules.
Pros & cons
What works
- 1911-style grip angle for familiar ergonomics
- Factory threaded barrel for suppressor compatibility
- Ambidextrous safety plus magazine disconnect
- Simplified one-button takedown for easy cleaning
Trade-offs
- 10-round magazines limit extended strings without a reload
- Threaded barrel adds length versus a standard flush barrel
- Suppressor use requires separate NFA approval and cost
Key attributes
| Transfer | Ships to your FFL dealer |
| Caliber | .22 LR |
| Capacity | 10+1 (2 magazines included) |
| Barrel Length | 4.4 in, threaded |
| Action | Semi-Automatic |
| Finish | Blue/Black |
Frequently asked questions
- Is this a complete pistol or just a barrel?
- It's a complete, ready-to-fire Ruger Mark IV 22/45 Tactical pistol (model 40149), not a standalone barrel or part.
- How many magazines come with it?
- Two 10-round magazines.
- Is the barrel threaded?
- Yes, 1/2x28 threading on the 4.4-inch stainless bull barrel, compatible with suppressors and other muzzle devices where legally permitted.
- What is the magazine disconnect safety?
- It prevents the pistol from firing when the magazine is removed, even if a round remains in the chamber.
- Does this ship to my home?
- No — as a complete firearm, it ships to a licensed FFL dealer for an in-person transfer and background check.